POS-601 QUALITY OF LIFE AND CLINICAL OUTCOMES OF HEMODIALYSIS PATIENTS IN A TERTIARY HOSPITAL IN METRO MANILA

Abstract

The incidence of ESRD requiring dialysis has been increasing worldwide across age group and exerts a negative impact on patient’s quality of life. This study aimed to assess the quality of life and clinical outcomes in different age groups of hemodialysis patients in a tertiary hospital. One hundred ten hemodialysis patients were included in this cross-sectional study. Subjects were classified based on the following age group: young adult (20 to 40 years old), middle adult (41 to 64 years old), young old (65 to 74 years old), middle old (75 to 84 years old) and old-old (85 years old and above). Overall and quality of life scores per age group was assessed using the Kidney Disease Quality of Life questionnaire (KDQOL-SFTM1.3). Mean and median scores for individual domain, overall health, summary component scores namely - physical(PCS), mental(MCS), kidney disease(KDCS) - were analyzed and compared to demographics and clinical data. The overall quality of life scores of hemodialysis patients were above average for overall health, mental component (MCS) and kidney disease component scores (KDCS) and borderline for physical component score (PCS). However, only overall health and MCS scores were statistically significant when compared per age group. Older adults (young old to old-old) had better quality of life compared to the young adults. Age, mode of treatment, type of vascular access, hemoglobin and phosphorus levels were found to have effects on at least one of the QOL scores. Hospitalization rate was not significantly different across age groups and did not affect the quality of life scores. Young adults on hemodialysis had the poorest quality of life based on KDQOL scores compared to their older counterparts. Component scores were noted to be improving almost directly proportional to age which could be attributed to age-related differences on disease perception and coping process.