POS-543 DO RENAL BIOPSIES ASSIST IN UNDERSTANDING OF LOIN PAIN HEMATURIA SYNDROME?

Abstract

Loin pain-hematuria syndrome (LPHS) first described in 1967, is a complex and poorly understood rare disease that predominantly affects young women. Patients with LPHS experience extreme flank pain along with hematuria in the absence of a primary kidney pathology. Due to inadequate understanding of the pathophysiology of LPHS, the goal of management has been limited to symptomatic relief and pain management. While it is uncertain if the source of pain and hematuria are interrelated, there is consensus that hematuria is glomerular in origin.