Abstract

Membranous nephropathy (MN) is the most prevalent cause of primary nephrotic syndrome amongst the adult population. The conventional option of first-line treatment for MN is the Modified Ponticelli Regimen (MPR). Discovery of the phospholipase A2 receptor (PLA2R) as a target antigen in patients with MN has brought new perspective in the management of this disease. B-cell depleting agents such as Rituximab have emerged as a treatment option. There is considerable debate whether Rituximab should be favored over MPR, due to its superior safety profile.

Full Text
Published version (Free)

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call