Abstract
Hypothyroidism in children with nephrotic syndrome (NS) is often attributed to prolonged loss of thyroxine binding globulin and thyroid hormones alongside protein in the urine. It has been historically associated with steroid resistant NS alone. However recent evidence supports subclinical hypothyroidism even in steroid responsive children with NS. Diverse complications can arise from hypothyroidism such as weight gain, hypercholesterolemia, delayed growth, delayed puberty, and depression which could all be erroneously attributed to NS or the effect of steroid in its treatment.
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