POS-180 OUTCOMES OF CONTINUOUS RENAL REPLACEMENT THERAPY (CRRT) INITIATED DURING CRITICAL PHASE OF SEVERE DENGUE IN CHILDREN - SINGLE TERTIARY CARE CENTRE EXPERIENCE FROM SOUTH INDIA

Abstract

Children with severe dengue experience excessive capillary leak during the critical phase of illness, whereas adults are more prone to severe bleeding. Fluid overload (F.O) is an undesirable event occurring in children with hypotensive shock, requiring large volumes of fluids for shock reversal. Existing literature on critically ill children suggests an F.O cut-off of >10% for intervention. As fluid overload is a major outcome determinant for critically ill children with severe dengue, early initiation of ultrafiltration combined with a target of negative fluid balance in the initial hours of CRRT may improve clinical outcomes.