POS-119 Factors That Influence Delayed Graft Function in Kidney Transplants: A Single-Center Paired Kidney Analysis

Abstract

Delayed graft function (DGF) is an early complication of kidney transplant which imposes several clinical factors related to donor, recipient and organ transplantation procedures. The aim of our study is to evaluate the risk factors of delayed graft function (DGF) and its impact on renal transplantation. We conducted a retrospective study consisting of 86 subjects who underwent kidney transplantation from 2010 to 2019. DFG was defined as requirement for dialysis within the first week after transplantation. DGF occurred in 7 of the 86 (8.1%) kidney transplant-recipients divided into 5 men and 2 women with a mean age of 42.4 +- 11.3 years. The causal nephropathy was mainly glomerular in 3 patients. patients received grafts from deceased donor in 4 cases. the dialysis duration was >12 months in all cases. 6 patients received immunosuppressant induction treatment based on anti-thymocyte globulin (4 patients) and basiliximab (2 patients). Mean warm and cold ischemic time was respectively at 35,33+-17 minutes and 21+-5.7 hours. At one-year post transplantation, the survival graft and patient rate was at 85.7%. Risk factors idenditified for DFG were: recipient age (p=0,05), hypertensive history (p=0,024), body mass index of recipient (p=0,027), deceased donor (p=0,000), living-related kidney transplantation donors (p=0,002), anti thymocyte globulin for induction therapy (p= 0,006) Understanding risk factors of DFG will help into the management of kidney transplantation and improve the outcomes by reducing this factors as much as possible.