Abstract
Acute kidney injury (AKI) is a frequent complication of children admitted to the paediatric intensive care unit(PICU) and is associated with significant short term and long -term consequences. One key management modality of AKI is the use of diuretics to reduce fluid overload which is an important indication for initiation of renal replacement therapy (RRT) - dialysis and also an important indicator of morbidity and mortality. Aminophylline, a drug that is well known for its use in the treatment of asthma is also purported to have diuretic effects.
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