Abstract
Congenital heart disease, related to the patent ductus arteriosus is one of the most important life-threating condition in human life. Administration of prostaglandin E1 to keep open the ductus arteriosus and fetal survival before corrective surgery is necessary. Despite the life-giving role of prostaglandin E1, numerous and dangerous side effects are considered; including the theories discussed, is effect of prostaglandin E1 on creation of hypercalciuria. This study is aimed to assess the effect of intravenous administration of prostaglandin E1 on calcium excretion in the urine of newborns with congenital heart disease.
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