Abstract
The portal vein thrombosis (PVT) is a partial or complete occlusion of blood flow through the portal vein that occurs due to the presence of a blood clot in its lumen. Currently, PVT has become more common in the clinic of internal diseases. PVT can be caused by many factors, among which local and systemic. Systemic factors include congenital and acquired thrombophilia. Local factors include inflammatory, infectious, and oncological diseases of the abdominal organs. One of the most likely causes of PVT is currently being considered liver cirrhosis. The article presents the literature data, clinical guidelines for managing patients with PVT in the discussion of three own clinical cases of patients with PVT, which were caused by various diseases.
Highlights
The article presents the literature data, clinical guidelines for managing patients with portal vein thrombosis (PVT) in the discussion of three own clinical cases of patients with PVT, which were caused by various diseases
PVT has become more common in the clinic of internal diseases
PVT can be caused by many factors
Summary
The article presents the literature data, clinical guidelines for managing patients with PVT in the discussion of three own clinical cases of patients with PVT, which were caused by various diseases. Отношение шансов (ОШ) развития ТВВ при наличии мутации Лейдена составляет 1,9, а мутации гена протромбина – 4,48 [1]. Примером развития ТВВ при системных нарушениях коагуляции может служить клинический случай пациентки Б., 35 лет, которая обратилась за медицинской помощью в мае 2015 г. При контрольном УЗИ органов брюшной полости и допплерографии (УЗДГ) гепато-лиенального кровотока выявлено расширение портальной и селезеночной вен, значительная спленомегалия (площадь 114 см2), асцит.
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