Portal vein embolization before hepatectomy in patients with inadequate future liver remnant. A single instituition experienceportal vein embolization before hepatectomy in patients with inadequate future liver remnant. A single instituition experience

Abstract

Introduction: To review our institution experience and outcome with portal vein embolization prior to hepatectomy in patients with inadequate future liver remnant. Method: We reviewed records of patients who underwent Portal Vein Embolization (PVE) at our institution between January 2010 to December 2017. Demographics, laboratory, embolization method and outcomes data were gathered. Comparison was done using Student T Test utilizing mean+-SD and Chi Square for proportion comparison. Result: 66 patients underwent PVE from 2010 till 2017 at our institution. 39 (60%) of patients who had PVE successfully underwent surgery and the majority was from the RPVE group. Most common embolic agent used in this study is Embozene and coils. Both the time interval between embolization and surgery and percentage of hypertrophy after embolization did not show statistical significance between RPVE and RPVE + Seg IV group. 34 patients underwent formal resection. 19(47%) had extended right hemihepatectomy while 37% had right hemihepatectomy. 6(16%) patients had local resection.2 major complication observed was 1 mortality due to Post Hepatectomy Liver Failure grade C and partial left portal vein thrombosis due to migration of embolic material. Conclusion: PVE is a safe procedure and benefits a selected cohorts of patients with inadequate future liver remnant.