Abstract

The usual conception of cirrhosis of the liver denotes any type of sclerosis in which there is destruction of liver cells associated with a real or apparent increase of connective tissue. The terms atrophic and referring to the size of the liver should be abandoned, since they do not indicate any definite disease entity but more a description of the stage of the disease. Early in the hypertrophic stages of the disease, exudation and necrosis of liver cells are the prominent features and replacement by the healing process is yet in the background. Later, when a large proportion of the necrotic liver cells have become replaced by scar tissue through a process of healing, the liver is decreased in size; this is usually designated as atrophic cirrhosis. Any type of cirrhosis of the liver in childhood is a rare disease, but the portal or Laennec type is especially uncommon

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