Abstract
10 patients with acute cholecystitis were studied with respect to presence of portal bacteremia. Cultures were concomitantly run also from peripheral venous blood, gallbladder and choledochal bile and peritoneum covering the cannulated mesenteric vein. In 2 cases <i>Escherichia coli </i>was recovered from portal vein blood and from gallbladder bile. <i>E. coli </i>was further found in peripheral blood from 1 of these patients and in peritoneum in the other. None of 12 patients undergoing elective cholecystectomy had portal bacteremia. The study indicates that portal venous blood normally is sterile. When portal bacteremia occurs in acute cholecystitis, cultures of gallbladder bile show the same organisms.
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