Abstract
Diversion of portal venous blood into the systemic circulation is associated with a high incidence of peptic ulcer in man. 1 Gastric secretory levels in patients with portacaval shunts are not above normal, but are probably elevated from preoperative values. 2 In the dog, portacaval shunting definitely enhances the rate of acid secretion by the stomach. 3 This has been shown to be due to a circulating substance, probably histamine. 4 The purpose of the present study was to determine, in the dog, changes in gastric, duodenal, pancreatic, and esophageal blood flows following creation of portacaval shunts. The radioisotope ( 42 K or 86 Rb) distribution method was used to measure tissue blood flows. Materials and Methods End-to-side portacaval anastomoses were constructed in nine healthy mongrel dogs. The control group consisted of 13 normal animals that had undergone no operation. All dogs were fed a standard diet of commercial dry cereal
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.