Abstract
An amperometric immunosensor based on a recombinant nucleocapsid antigen has been developed for fast determination of antibodies against Sin Nombre (SN) virus in human blood serum. This approach combines the advantages of utilization of highly dispersed immunosorbent, with highly sensitive electrochemical detection of enzyme-marker, and flow-injection scheme of immunoassay. A main benefit of recombinant nucleocapsid antigen is that antigen preparation and standardization is easy. The complete immunoassay can be performed in 24 minutes. The short overall assay time could be a major advantage in the field of diagnostic screening of infectious diseases in mobile laboratories and small hospitals. The immunosensor has been successfully used in the determination of anti-Hantavirus IgG in human blood plasma and is easily adaptable for the detection of other types of viral infections.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
