Abstract

Immunofluorescence is one of the primary techniques for microbiological assays. Although it has existed for decades, its usages in medical and biological practices have limitations that need to be tackled with, especially the need of increasing its portability and specificity, and lowering its detection limit. A portable optical fluorescence system was designed to be combined with a direct digital synthesizer for surface acoustic wave generation. Rayleigh wave streaming generated on a piezoelectric device is able to prevent nonspecific binding on the biological interface. The miniaturized prototype, integrating acoustic wave removal of interfering proteins combined with optical detection, was developed to realize immune-detection on a portable platform.

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