Abstract
Coronary heart disease (CHD) is the leading cause of death among patients with type 2 diabetes. Several factors were observed to be associated with an increased risk of major manifestations of CHD. Elevated levels of C-reactive protein (CRP), although often in the healthy reference range, have been associated with increased risk of future CHD (1). We hypothesized that periodontal infection might contribute to the elevated CRP in diabetic populations, since periodontal disease has recently been declared the sixth complication of diabetes (2). Serum IgG antibody levels against several periodontal pathogens, especially against Porphyromonas gingivalis ( P. gingivalis ), are elevated …
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