Abstract
Porphyria cutanea tarda (PCT) is the most frequent type of porphyria worldwide and presents with skin symptoms only. Porphyrias are a group of eight panethnic inherited metabolic disorders of heme biosynthesis. Porphyria can affect peripheral, autonomic, and central nervous systems.In porphyria conditions there is accumulation of the hemeprecursor's 5-aminolaevulinic acid, porphobilinogen, and porphyrins; which are associated with characteristic clinical feature with acute neurovisceral attacks and skin lesions. Variegate porphyria, hereditary coproporphyria, and PCT share the same chronic cutaneous photosensitivity. Some drugs will also induce acute attack of porphyria. This report summarizes the management of PCT with a focus on the signs and symptoms and finding that might help and prevent unnecessary medications.
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