Abstract
Porous hydroxyapatite (HA) microspheres with the main particle size of 42–50μm were fabricated using a novel ITSD technique. Pore structures transformed from aligned pores to cellular pores, with the increase of PVA contents. The percentages of GS loadings decreased from 41.8% to 30.9%, with porosities decreasing from 58.7% to 40.2%. Gentamicin was successfully loaded into porous HA microspheres and about 80% of loaded-GS amount was released from GS-loaded HA microspheres during 48h period.
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