Abstract
In this study, we successfully synthesized Cux Coy S supraparticles (SPs) on the nanoscale featuring multiple pores inside and strong absorption from 400 to 900 nm. Porous Cux Coy S SPs produced the highest reactive oxygen species (ROS) yield (1.39) when illuminated with near-infrared (NIR) light. Furthermore, we demonstrated that Cux Coy S SPs could be used to identify cancer cells through intracellular telomerase-responsive fluorescence (FL) imaging in living cells. Because the Cux Coy S SPs were associated with telomerase-responsive bioimaging and high ROS production, they can be efficiently used in the diagnosis and therapy of tumors with high selectivity and excellent therapeutic effects in vivo. This study provides a new vision for the creation of multifunctional SPs, which can be used as cellular sensors and control tools for pathologies across a broad range of biological systems.
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