Porous cuprous oxide microcubes for non-enzymatic amperometric hydrogen peroxide and glucose sensing

Abstract

Using porous cuprous oxide (Cu 2O) microcubes, a simple non-enzymatic amperometric sensor for the detection of H 2O 2 and glucose has been fabricated. Cyclic voltammetry (CV) revealed that porous Cu 2O microcubes exhibited a direct electrocatalytic activity for the reduction of H 2O 2 in phosphate buffer solution and the oxidation of glucose in an alkaline medium. The non-enzymatic amperometric sensor used in the detection of H 2O 2 with detection limit of 1.5 × 10 −6 M over wide linear detection ranges up to 1.5 mM and with a high sensitivity of 50.6 μA/mM. This non-enzymatic voltammetric sensor was further utilized in detection of glucose with a detection limit of 8.0 × 10 −7 M, a linear detection range up to 500 μM and with a sensitivity of −70.8 μA/mM.