Abstract
Our objective is invention of new medical products in Thailand by Thai scientists, for human bone substitute, from cow bone. In the previous research experiments, the cow bone-calcium phosphate glass composites had adequate scientific properties to be used as medical objects including, 95% of principal molecules were inorganic hydroxyapatite, no contaminating dangerous heavy metal over standard limits (cadmium,arsenic,mercury,lead), high vertical compressive strength (more than 400 kg/cm2), and no adverse reactions inside the laboratory animals. In this research, we made cranialfixator buttons from bovine bone-calcium phosphate glass composites, intended for neurosurgical skull closure, tested in 10 patients and follow up for at least 6 months. The results revealed that our inventions have easily performance, really effectiveness,and entirely non-complications.
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