Porokeratoma treated with topical 5% 5-fluorouracil cream.

Abstract

What is known about this subject in regard to women and their families? • Porokeratoma is a rare lesion with distinct pathologic features that make diagnosis challenging. • Porokeratoma has historically been treated with excision. • In those who are cosmetically sensitive, particularly women, excision may not be a desirable treatment option. What is new from this article as messages for women and their families? • Porokeratoma can be successfully treated with topical 5% 5-fluorouracil (5-FU) cream. • Topical 5-FU is a safe and practical alternative to surgical intervention, especially in patients who are cosmetically sensitive. It is also useful in sites, such as the hands, where excision can compromise daily functioning and occupational activities.