Abstract
The hyaline or “fibrinoid” material deposited in glomerular capillaries and minor vessels of the corium in association with swine salmonellosis, an experimental model of the generalized Shwartzman reaction, was found to be derived predominantly from disintegrated red blood cells. Severe stasis with excessive vasodilatation preceded the erythrocytic damage. Massive haemolysis did not seem to take place; the stagnant and tightly packed red cells in the engorged vessels were submitted to various types of disintegrating processes, the ultimate result being partial lysis. It is suggested that this erythrocytic debris corresponds to the hyaline masses which frequently stain as fibrin in conventional histological sections.
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