Abstract
We report a novel model of arterial tortuosity in the porcine brachial artery for testing of endovascular devices in the flexed forelimb position. This provides an ideal vascular territory for an in vivo assessment of guidewires, microcatheters, and endovascular implants because it closely mimics the challenging curvature at the carotid siphon.
Highlights
Advances in interventional neuroradiology are reshaping the treatment paradigms and have facilitated the development of a wide array of endoluminal techniques for vascular lesions that were earlier only approachable neurosurgically
We describe a porcine brachial artery tortuosity model to provide a challenging vascular territory for endovascular device testing
Forceful catheterization of the carotid siphon can result in thrombosis and vasospasm as a result of endothelial injury
Summary
Porcine Brachial Artery Tortuosity for In Vivo Evaluation of Neuroendovascular Devices. SUMMARY: We report a novel model of arterial tortuosity in the porcine brachial artery for testing of endovascular devices in the flexed forelimb position. This provides an ideal vascular territory for an in vivo assessment of guidewires, microcatheters, and endovascular implants because it closely mimics the challenging curvature at the carotid siphon. The positioning of the forelimb in the flexed position increased the number of tortuous bends in comparison with the extended position (Fig 1, On-line Video) and emphasized the complexity of the curvatures This arterial territory allows a successful navigation and testing of an array of endovascular devices like guidewires, microcatheters, endovascular stents, and delivery systems
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