Abstract
Using next-generation sequencing, we identified and genetically characterized a porcine astrovirus type 3 strain found in tissues from the central nervous system of 1 piglet and 3 sows with neurologic signs and nonsuppurative polioencephalomyelitis. Further studies are needed to understand the potential for cross-species transmission and clinical impact.
Highlights
Dr Walz is a researcher in the Department of Veterinary and Biomedical Sciences, College of Veterinary Medicine, at the University of Minnesota
Using next-generation sequencing, we identified and genetically characterized a porcine astrovirus type 3 strain found in tissues from the central nervous system of 1 piglet and 3 sows with neurologic signs and nonsuppurative polioencephalomyelitis
We describe the use of unbiased next-generation sequencing to identify and genetically characterize a porcine astrovirus type 3 (PoAstV-3) in central nervous system (CNS) tissues of a 5-week-old piglet and 3 sows with neurologic signs and histopathologic lesions compatible with a neurotropic viral infection
Summary
Hensch); São Paulo State University (Unesp), Jaboticabal, Brazil (I.R.H. Gatto); Cambridge Technologies, Worthington, Minnesota, USA Using next-generation sequencing, we identified and genetically characterized a porcine astrovirus type 3 strain found in tissues from the central nervous system of 1 piglet and 3 sows with neurologic signs and nonsuppurative polioencephalomyelitis.
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