Abstract
Neuroimaging offers a valuable insight into human brain development by allowing in vivo assessment of structure, connectivity and function. Multimodal neuroimaging data have been obtained as part of three sub-studies within the Avon Longitudinal Study of Parents and Children, a prospective multigenerational pregnancy and birth cohort based in the United Kingdom. Brain imaging data were acquired when offspring were between 18 and 24 years of age, and included acquisition of structural, functional and magnetization transfer magnetic resonance, diffusion tensor, and magnetoencephalography imaging. This resource provides a unique opportunity to combine neuroimaging data with extensive phenotypic and genotypic measures from participants, their mothers, and fathers.
Highlights
Population neuroscience, the interface between epidemiology and neuroscience, aims to identify environmental and genetic factors associated with brain health across the lifespan1,2
The inception of large-scale population based studies3–10, and those embedded in existing cohorts9,11, has generated a rich source of neuroimaging data drawn from the general population
We present three such studies nested within The Avon Longitudinal Study of Parents and Children (ALSPAC)12–14
Summary
Grant information: The UK Medical Research Council and Wellcome (Grant ref: 102215/2/13/2) and the University of Bristol provide core support for ALSPAC.
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