Population data and mutation rate of nine Y-STRs in a mestizo Mexican population from Guadalajara, Jalisco, México

Abstract

Nine Y-STR (DYS19, DYS390, DYS391, DYS392, DYS446, DYS447, DYS448, DYS456 and DYS458) were analyzed in a male sample of 285 unrelated individuals from Guadalajara, Jalisco, México. The haplotype diversity (0.996) and discrimination capacity (0.986) were calculated. A family study of around 200 father/son pairs and among 1828 meiosis showed five mutational events. All mutations were single step. The overall mutation rate estimated across the nine Y-STRs was 2.7 × 10 −3 (95% CI 1.2–6.4 × 10 −3)/ locus/meiosis. The results indicate that these nine loci are useful Y-linked markers for forensic applications.