Abstract
In recent years, the range of combined narcotic drugs has widened. New chemical modifications have emerged, including so-called designer drugs, whose action on the body and in particular on the state of vision is increasingly difficult to determine. While the problem of drug abuse is growing drastically, timely detection of a possible toxic damage to the eye induced by drugs and reliable diagnosis differentiating such damage from other etiologies becomes a topical practical issue. The paper presents a clinical case of poppers maculopathy (poppers being a slang name of aromatic volatile alkyl nitrite compounds). Ophthalmological manifestations and differential diagnostic criteria of the damage are described. The mechanisms of action and possible treatment methods are discussed.
Highlights
In recent years, the range of combined narcotic drugs has widened
The paper presents a clinical case of poppers maculopathy
ЗАКЛЮЧЕНИЕ Своевременное распознавание «попперс»-макулопатии необходимо в связи с проведением дифференциальной диагностики с фотохимическим повреждением сетчатки при воздействии солнечных лучей или сварочной дуги (solar retinopathy, Welder's maculopathy), фототермическим поражением при использовании высокомощных лазерных указок (laser pointer maculopathy) из-за сходной клинической картины и структурных изменений на сканах Оптическая когерентная томография (ОКТ), а также для информирования пациента о потенциальной токсичности данной группы наркотических средств для зрительного анализатора и важности отмены их употребления
Summary
The range of combined narcotic drugs has widened. New chemical modifications have emerged, including so-called designer drugs, whose action on the body and in particular on the state of vision is increasingly difficult to determine. При анализе толщины сетчатки (ILM-RPE) в макуле нитрит или амилнитрит по отдельности или в комбинации по протоколу Macular Cube 512 × 218 выявлено двусторон- Алкилнитриты, отмечается увеличение числа сообщений о развитии зри- являясь донорами оксида азота, могут оказывать прямое токтельных нарушений в результате острой и хронической сическое воздействие на фоторецепторы сетчатки, которые интоксикации алкилнитритами.
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