Abstract
BackgroundSleep disturbances are frequently reported among people living with HIV infection. In Ethiopia, approximately half of people living with HIV/AIDS experience mental health issues, which further degrade sleep quality. This systematic review and meta-analysis aims to assess the national prevalence of poor sleep quality and identify key determinants.MethodsA systematic review and meta-analysis followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, focusing on English-published studies. The search spanned Google Scholar, HINARI, Scopus, PubMed, EMBASE, Web of Science, and AJOL from April 4, 2023, to May 15, 2023. Three reviewers independently extracted data and evaluated study quality using a modified Newcastle‒Ottawa scale for cross-sectional studies. Stata version 11 was used for the meta-analysis, employing a random-effects model to estimate poor sleep quality. Study heterogeneity was assessed using I2 and Cochran's Q test.ResultsA total of 6,070 articles regarding poor sleep quality and/or associated factors among people attending antiretroviral treatment clinics in Ethiopia were retrieved. The pooled estimate of poor sleep quality among people living with HIV in Ethiopia was 52.64 (95% CI: 44.08, 61.20). Depression (AOR = 4.61; 95% CI: 1.15, 18.51), a CD4 count < 200 cells/mm3 (AOR = 1.83; 95% CI: 0.33, 10.18), a viral load > 1000 copies (AOR = 1.42; 95% CI: 0.19, 10.61), and anxiety (AOR = 17.16; 95% CI: 4.47, 65.91) were identified as factors associated with poor sleep quality.ConclusionA systematic review and meta-analysis found that about half of people living with HIV/AIDS in Ethiopia experience poor sleep quality. Key factors contributing to poor sleep quality include CD4 count, viral load, depression, and anxiety. Policymakers and relevant organizations should address these issues to improve sleep quality and manage the factors affecting it.
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