Abstract
An increased rate of non-righthandedness and other abnormalities of lateralization have been reported in schizophrenia. We investigated childhood hand preference and eye dominance as risk factors for adult schizophrenia among a general population birth cohort. Pre-schizophrenic children showed a significant excess of left-eye dominance at age 11 when compared with controls (OR 2.5, 1.0–5.8, p=0.03), but there was no significant difference in hand preference between pre-schizophrenic children and controls.
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