Poor response to therapy for bullous pemphigoid lesions located on the hemiplegic half of the body

Şirin Yaşar,Pembegül Güneş,Fatih Göktay,Sema Aytekin,Dua Cebeci

doi:10.15761/god.1000174

Abstract

Poor response to therapy for bullous pemphigoid lesions located on the hemiplegic half of the body

Highlights

Bullous pemphigoid (BP) is an autoimmune disease prevalent in elderly patients characterized by the formation of subepidermal blisters or bullae
Previous studies and case reports have suggested that neurological disorders, such as dementia, Parkinson’s disease, and multiple sclerosis, may be associated with BP and that the age of BP occurrence can range from 1.5 years to 60 years
In neurological diseases associated with BP, AG1 is a common antigen that can play a role in BP pathogenesis, with BpAG1a occurring in neural tissue, BpAG-1b in muscle, and BpAG-1e in the skin

Summary

Introduction

Bullous pemphigoid (BP) is an autoimmune disease prevalent in elderly patients characterized by the formation of subepidermal blisters or bullae. BP may be associated with autoimmune diseases, inflammatory dermatoses, malignancies, or neurological disorders. In particular, have been reported in association with BP, including cerebrovascular disease, dementia, multiple sclerosis, epilepsy, Parkinson’s disease, Shy Drager syndrome, and amyotrophic lateral sclerosis [1,2,3].

Results

Conclusion