Abstract
This work presents the synthesis of polyvinylpyrrolidone (PVP) and chitosan (CS) coated magnetite (Fe3O4) nanoparticles (NPs) by co-precipitation technique. The objective of this research was to investigate the catalytic, antibacterial efficacy with evidential molecular docking analysis of CS/PVP- Fe3O4 and PVP/CS- Fe3O4. The coating of PVP and CS reduced the particle size of Fe3O4, providing a large surface area that increased catalytic and antibacterial potency. These binary coated magnetite NPs used as ideal catalytic agent for the reduction of rhodamine B dye as well as antibacterial agent against Escherichia coli. The findings of a molecular docking investigation were in reasonable accord with in vitro microbicidal activity and revealed that CS-Fe3O4, Fe3O4-doped PVP and CS are promising inhibitors of dihydrofolate reductaseE. Coli (DHFR) and DNA gyraseE. Coli.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have