Abstract
Received Aug. 3, 2001; revision received Jan. 24, 2002; accepted Feb. 13, 2002. From the Department of Psychiatry and Psychology and the Department of Infectious Diseases, Cleveland Clinic Foundation, Cleveland. Address reprint requests to Dr. Franco, P57, Department of Psychiatry and Psychology, Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH 44195; francok@ccf.org (e-mail). Copyright 2002 The Academy of Psychosomatic Medicine. Despite clozapine’s efficacy, there are occasions when switching medication is indicated and a slow taper to avoid withdrawal is recommended. We report the consequences and treatment of abrupt discontinuation of clozapine in a male patient with schizoaffective disorder.
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