Abstract
A new method has been employed for preparation of silver nanoparticles (Ag-NPs) in polyelectrolyte hydrogels (PEHs) composed from polysaccharides such as xanthan gum (XG) and chitosan (CS) without using other organic solvents and reagents. The present study allows a simple and ecofriendly synthesis of Ag-NPs within PEHs network and were confirmed by UV–visible spectra with characteristic surface plasmon band in the range of 398–409nm using different concentrations of silver ions. Highly controllable Ag-NPs with diameters of around 5–20nm were obtained in PEHs with spherical shape. Scanning electron microscopy results confirmed that the Ag-NPs were formed homogeneously in the PEHs. Antibacterial activity of PEHs containing Ag-NPs has a great inhibition towards both gram-positive Staphylococcus aureus and negative-bacteria Escherichia coli. In vitro cytotoxicity and cell attachment studies with NIH 3T3 fibroblast cells on PEHs showed good cytocompatibile and that may be possibly used in antibacterial wound dressing applications.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
