Abstract
A solid phase membrane adsorbent—a nylon 6 nanofibers membrane coated by polypyrrole (PPy-PA6-NFsM)—was firstly synthesized and used for extraction of two β-lactam antibiotics (oxacillin and cloxacillin) in urban river water. Then the analytes were detected by capillary electrophoresis with a diode array detector (CE-DAD). The synthesized nanofibers membrane was characterized by scanning electron microscopy and a Fourier transform infrared spectrometer. The experimental conditions were optimized, including the amount used of PPy-PA6-NFsM, pH of the sample solutions, adsorption volume, and desorption conditions. Under the optimal extraction and separation conditions, the detection limits were found to be 2.0 ng/mL for both oxacillin and cloxacillin. The proposed method was applied to the determination of the two β-lactams in water samples of an urban river. The recoveries of these two β-lactams were found to be in the range 84.2–96.4%, demonstrating that PPy-PA6-NFsM has a high extraction capability for these two antibiotics. The relative standard deviations, ranging from 2.26% to 5.29% for intraday measurements and from 2.38% to 7.02% for inter-day determinations, were derived respectively.
Highlights
Antibiotics are an important group of pharmaceuticals and personal care products, which have been extensively used in human therapies and veterinary medications, as well as in aquaculture [1].Incomplete removal and improper waste disposal can lead to the release of these excreted antibiotics into the aquatic environment by various pathways [2]
Increasing attention has been paid to the generation and environmental spread of antibiotic resistance genes (AGRs) due to overuse of various antibiotics [4]. β-lactam antibiotics have been used in treatments of a variety of bacterial infections, including gram-positive bacteria as well as some gram-negative bacteria [5]
A possible explanation is that the concentrations of the antibiotic residues in water samples were below the detection limits
Summary
Antibiotics are an important group of pharmaceuticals and personal care products, which have been extensively used in human therapies and veterinary medications, as well as in aquaculture [1]. Such kind of adsorbents were used for removal of toxic dyes and arsenite from aqueous solutions [20,21], and extraction of steroids and non-steroidal anti-inflammatory drugs from aqueous solutions [20,21], and extraction of steroids and non-steroidal anti-inflammatory drugs from water samples [22,23] They were applied for extraction of cortisol from human hair [24]. PPy has been coated on PA6-NFsM and the modified nanomaterial (PPy-PA6for extraction of oxacillin (OXA) and cloxacillin (CLOX) from urban water samples has been exploited. The established method has been applied for the determination of the two antibiotics in actual water samples.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
