Abstract
The preparations from selected traditional medicinal plants in Poland ( Asteraceae and Rosaceae families), were prepared in the multi-step process of isolation and their anticoagulant activity was measured by APTT and PT tests. The most promising effect was observed for the substances extracted from Fragaria vesca ( Rosaceae) and Echinacea purpurea ( Asteraceae). They showed interesting activity with respect to the activity of 5th International Standard for Unfractionated Heparin in APTT method. The structure characterization by IR, HPLC, GLC-MS and colorimetric methods revealed that these preparations are macromolecular polysaccharide–polyphenolic conjugates, similar to cell wall acidic macromolecular fragments which are common in the higher plants. The high content of hexuronic acids, as well as phenolic glycoconjugates seems to be responsible for the observed anticoagulant activity.
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
