Abstract
Quorum sensing (QS) is an intercellular signaling and gene regulatory mechanism, which is implicated in bacterial pathogenicity and food spoilage. Therefore, blocking bacterial QS system may prevent QS-controlled phenotypes responsible for food spoilage. In the present study, we aimed to investigate the anti-biofilm and quorum sensing inhibitory potentials of Rosa rugosa tea polyphenol (RTP) extract, which is rich in polyphenols (87.52%) and flavonoids (61.03%). The RTP specifically inhibited QS-controlled violacein production in Chromobacterium violaceum 026 with 87.56% reduction without significantly affecting its growth. Moreover, RTP exhibited inhibition in swarming motility (84.90% and 78.03%) and biofilm formation (67.02% and 72.90%) of Escherichia coli K-12 and Pseudomonas aeruginosa PAO1 in a concentration-dependent manner, respectively. These findings strongly suggest that RTP potentially could be developed as a new QS inhibitor and/or anti-biofilm agent to enhance the shelf life and increase food safety.
Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
