Abstract

Abstract Five new polyoxygenated steroids 1–5 have been isolated from a Formosan soft coral Sinularia facile. The structures of new metabolites were elucidated on the basis of extensive spectroscopic analysis and cytotoxic activity of 1–5 against the proliferation of a limited panel of cancer cell lines was measured. Metabolite 4 has been shown to exhibit weak cytotoxicity against Hep G2, Hep G3B, MDA-MB-231, and Ca9-22 cancer cell lines.

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