Abstract

Polyomaviruses KI (KIPyV) and WU (WUPyV) were recently identified, mainly in respiratory specimens from children. Among 200 patients with respiratory disorders admitted to Saint Louis Hospital, Paris, France, KIPyV was detected in 8% and WUPyV in 1%. KIPyV was significantly more frequent among human stem cell transplant patients (17.8% vs. 5.1%; p = 0.01).

Highlights

  • Polyomaviruses KI (KIPyV) and WU (WUPyV) were recently identified, mainly in respiratory specimens from children

  • The Study From January through June 2007, 265 respiratory samples were received in the laboratory of Saint Louis Hospital, Paris: 154 nasal aspirates (NA) and 111 bronchoalveolar lavage (BAL) specimens collected from 200 patients with suspected upper or lower respiratory tract infections

  • The detection of KIPyV was significantly more frequent among hematopoietic stem cell transplant (HSCT) recipients than among other patients (17.8% [8/45] vs. 5.1% [8/155], p = 0.01) (Table)

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Summary

Polyomaviruses KI and WU in Immunocompromised Patients with Respiratory Disease

We examined the prevalence of KIPyV and WUPyV in immunocompromised patients with suspected respiratory tract infections. The Study From January through June 2007, 265 respiratory samples were received in the laboratory of Saint Louis Hospital, Paris: 154 nasal aspirates (NA) and 111 bronchoalveolar lavage (BAL) specimens collected from 200 patients with suspected upper or lower respiratory tract infections. This hospital specializes in the management of immunocompromised patients. 1 HSCT patient who experienced diarrhea demonstrated persistent excretion of KIPyV in 9 consecutive stool specimens collected between June and the end of November 2007 (data not shown)

Conclusions
Findings
Other patients
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