Abstract

After Giulio Bizzozero in 1882 first reported the simultaneous involvement of leukocytes and platelets in thrombus formation [1], the presence of polymorphonuclear leukocytes (PMN) in hemostatic platelet plug and arterial thrombi has been repeatedly observed by microscopy. The general consensus however was that these cells were only playing a passive role in thrombus formation but were likely involved in the subsequent repair process.

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