Abstract
Background Primary or transmitted HIV-1 drug resistance has caused an alarm in developed countries. While certain HIV-1 subtype C polymorphisms in relation to consensus subtype B sequences are known, there still exists a debate on the validity of these mutations being associated with/mistaken as, primary resistance. In this preliminary study, we have determined polymorphisms in reverse transcriptase (RT) and protease (PR) genes of HIV-1 subtype C from Mumbai, India.
Highlights
Primary or transmitted HIV-1 drug resistance has caused an alarm in developed countries
While certain HIV-1 subtype C polymorphisms in relation to consensus subtype B sequences are known, there still exists a debate on the validity of these mutations being associated with/mistaken as, primary resistance
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Summary
Polymorphisms in reverse transcriptase and protease genes of HIV-1 subtype C from Mumbai. Ritwik Dahake*, Shraddha Mehta, Sneha Yadav, Abhay Chowdhary, Ranjana A Deshmukh. From 2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014) Chennai, India. From 2nd International Science Symposium on HIV and Infectious Diseases (HIV SCIENCE 2014) Chennai, India. 30 January - 1 February 2014
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