Abstract
We analysed the impact of envelope glycoprotein gp41 polymorphism on the persistence of long-term nonprogressor (LTNP) status in 59 HIV-1-infected individuals over a period of time exceeding 6 years. The presence of a leucine at the codon 830, instead of the predominant isoleucine residue, was significantly associated with nonprogression, independently of the presence of two particular classes of antigp41 antibodies (antigp41 IgG2 and anti-SWSNKS peptide) previously reported as markers of LTNP status.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.