Abstract
The fibrous sheath (FS) is a unique sperm tail periaxonemal structure, surrounding the axoneme in the principle part of the flagellum. It is known that the motility of sperms is provided mostly by glycolysis (1). Spermspecific glyceraldehyde-3-phosphate dehydrogenase (GAPDHS), one of the enzymes of glycolysis, is tightly associated with FS (2). Oxidation of GAPDHS decreases sperm motility (3). The goal of the present work was to investigate of the gene GAPDHS in sperm samples of the patients with rare form of astenozoospermia - dysplasia of the FS (DFS), presumably of genetic origin.
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