Abstract
Background and Aims : Coronary artery disease (CAD) is the narrowing of the lumen of coronary arteries due to deposition of plaque. Extensive research has identified a large number of genetic markers predisposing to CAD. Proprotein convertase subtilisin/kexin type 9 is an enzyme that degrade LDL receptors which results in decreased LDL clearance from blood, however loss of function mutations in its gene do the reverse. One such loss of function PCSK9 variant is rs11591147 also known as G137T or R46L.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
