Abstract
ABSTRACTWe studied the physico/chemical effects of deep UV irradiation of polystyrene, PMMA and polycarbonate with respect to cell adhesion and protein immobilization. Photochemical modifications of the polymer surfaces yielded unstable peroxides and carboxylic acid groups. Patterned protein adsorbates were realized by coupling via carbodiimid activation of the COOH moieties. We have immobilized enzymes and antibodies. It was observed that hepatoma cells (HepG2) and fibroblasts (L929) adhered in the presence of serum proteins in the culture medium on the irradiated regions of the substrate without any further treatment.
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