Abstract
During the window of implantation (WOI), highly complex biological events take place, and despite the developments in assisted reproduction, recurrent implantation failures (RIF) are still inevitable. This study has aimed to construct a 3D environment by using artificial and natural biomaterials to promote the implantation of a blastocyst by providing an imitated natural profile of the endometrium in vitro to evaluate the chance of use of such material in RIF, and understand the background mechanism of implantation.
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