Abstract
Wound healing is a complicated procedure which necessitates laying out a suitable wound healing system or dressing which possesses key factors like a wet wound location, avoidance of microbial action and absorption of exudates. Various wound dressings can be accessible but not all can meet the particular conditions of a perfect wound healing system to complete proper wound healing process. Poly(Lactic Acid) (PLA) Nano Structure Mats are a new class of materials that possess great potential in wound healing because of biocompatibility, bio absorbability, biodegradability, absorption of exudates from the wound, physical safety of the wounded tissue and the probability to free useful molecules. Our review article gives a brief intro on the wound and skin structure and afterwards gives information about the peerless characteristics of PLA Nano Structure Mats remarkable for wound healing. Moreover, new recent investigations about PLA Nano Structure Mats usage for wound healing applications were also explored.
Highlights
Wound is every damage and break in the skin surface and/or the disruption of living tissue integrity of the skin or mucosa as a result of factors such as cuts, burns, trauma, illness or other impacts etc
If the wound is not properly protected and covered, unwanted infections can generate leading to further health hazards and illnesses
Poly(Lactic Acid) (PLA) Nano Structure mats have been utilized in a vast diversity of forms like nanofibers, porous scaffolds, composite nanofibres containing drugs and additives, porous scaffolds combined with drugs or plant additives which will be reported in detail at below
Summary
Wound is every damage and break in the skin surface and/or the disruption of living tissue integrity of the skin or mucosa as a result of factors such as cuts, burns, trauma, illness or other impacts etc. Wound dressing is a sterile pad or compress implemented to a wound in order to support healing and mainly protect the wound from further possible harms. 3 main layers named as the hypodermis, the dermis and the epidermis form the skin [1]-[3]. A wound can be resulted from physical, chemical, mechanical and thermal harms (Figure 2) [10]-[12]. In another words, an interruption of normal anatomic relationship and role of the skin can be called as wound [13],[14]. Acute wounds could be resulted from traumas, yet these wounds are generally repairable in eight to twelve weeks [17]. Four overlying and mutually dependent periods: hemostasis and coagulation, inflammation, proliferation and re-modeling constitute the typical healing method for a wound [17],[35]-[37]
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