Abstract
A simple and highly efficient method has been developed for the construction of polyhydroquinoline derivatives via one-pot, four-component Hantzsch condensation of various aldehydes, dimedone, ethyl acetoacetate, and ammonium acetate in the presence of an ionic liquid, 1-sulpopyridinium chloride, as a catalyst under solvent-free conditions. This methodology has an advantage of high yields, short reaction times, a clean reaction profile, and reusability of the catalyst.
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