Polygonum capitatum Buch.-Ham. ex D. Don: a review of its phytochemistry

Yang Yang,Bin Zhu,Zhonghai Zhou,Qian Hong,Jie Yang

doi:10.1590/fst.110021

Yang Yang, Bin Zhu + Show 3 more

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https://doi.org/10.1590/fst.110021

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Abstract

Polygonum capitatum (Polygonaceae) exists in rural areas of Southwest China and some other Asian countries. Its aerial part or whole herbal plant has been used as a Miao ethnomedicine against urinary system diseases, infections, pyelonephritis, diarrhea, and so on. The progress in phytochemical research on P. capitatum over the past decades is summarized. Two hundred and three chemical constituents that have been isolated and identified from this plant are included in this article, the chemical structures of which include aliphatic hydrocarbons, aliphatic alcohols, aliphatic ketones, aromatic aldehydes, aliphatic acids, glycerides, triterpenic acids, sterols, anthraquinones, chromones and their glycosides, flavonoids and their glycosides, phenols, phenolic acids and their esters, lignanoids, flavonolignans, phenolic glycosides, alcoholic glycosides, amino acids, nucleobases, amides, alkaloids, alkyl glycosides, volatile oils, and polysaccharides.

Highlights

Practical Application: The results of this review provide reference for further research and application of P. capitatum and related preparations
Tablets and capsules (Figure 3), which are prepared from P. capitatum and approved by the Chinese Food and Drug Administration (Zhang et al, 2013a), have the efficacy of “clearing away heat”, “reducing fire”, “dredging stranguria”, and diuresis, and are used to treat frequent and urgent urination, dysuria, urinary tract infections and pyelonephritis (National Pharmacopoeia Committee, 2020)
Research had showed that the chemical constituents of P. capitatum include sterols, triterpenes, alkaloids, lignans, flavonoids, phenolic acids (Chen et al, 2010b; Gao et al, 2001; Li et al, 2000, 2007; Liao et al, 2013; Liu et al, 2008; Wang et al, 2013; Yang et al, 2011, 2015b; Yu et al, 2008; Zhang et al, 2010; Zhao et al, 2010), and other volatile oils (Gao et al, 2005; Wang et al, 2007) and liposoluble compounds (Yang et al, 2009, 2011)

Summary

Introduction

Research had showed that the chemical constituents of P. capitatum include sterols, triterpenes, alkaloids, lignans, flavonoids, phenolic acids (Chen et al, 2010b; Gao et al, 2001; Li et al, 2000, 2007; Liao et al, 2013; Liu et al, 2008; Wang et al, 2013; Yang et al, 2011, 2015b; Yu et al, 2008; Zhang et al, 2010; Zhao et al, 2010), and other volatile oils (Gao et al, 2005; Wang et al, 2007) and liposoluble compounds (Yang et al, 2009, 2011). The chemical structures include aliphatic hydrocarbons, aliphatic alcohols, aliphatic ketones, aromatic aldehydes, aliphatic acids, glycerides, triterpenic acids, sterols, anthraquinones, chromones and their glycosides, flavonoids and their glycosides, phenols, phenolic acids and their esters, lignanoids, flavonolignans, phenolic glycosides, alcoholic glycosides, amino acids, nucleobases, amides, alkaloids, alkyl glycosides, volatile oils, and polysaccharides

Results and discussions

Conclusions

Conflict of interest