Abstract
Polyethylene glycol (PEG) in water is found to be an inexpensive, non-toxic and eco-friendly reaction medium for the nucleophilic addition of trimethylsilyl cyanide (TMSCN) to imines (Strecker reaction) to afford α-aminonitriles in excellent yields. This protocol is effective to a wide variety of substrates with different functional groups and does not require the use of acid or base catalyst. PEG can be recovered and reused.
Full Text 
Sign-in/Register to access full text options
Sign-in/Register to access full text options 
Published version (
Free)
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
